Stereochemistry

Biography

Plato A. Magriotis, Ph.D., is an Associate Professor of Medicinal Chemistry at the Department of Pharmacy, School of Health Sciences at the University of Patras in Greece and a Research Affiliate with the Department of Chemistry at New York University since 2006. Magriotis received his Ph.D. in Chemical Biology working with Professor Francis Johnson at the Department of Chemistry of Stony Brook University in 1983 and did Postdoctoral work at Harvard University with Nobel Laureate E. J. Corey. He began his academic career at West Virginia University and when presented with a very attractive offer to join Merck & Co. as a senior scientist, he joined the Medicinal Chemistry Department of Merck Pharmaceutical Company in New Jersey. Before assuming his present position, he moved back to Academia as an Adjunct Professor of Chemistry at New York University in 2002. Magriotis’ research program focuses on the development of new methodology for the synthesis of relevant pharmacophores applied in drug discovery.

Research Interest

•Synthesis of biologically and pharmacologically relevant molecules such as alpha and beta amino acids, beta lactams, piperidines, and piperazines. •Total Synthesis of antitumor, antibiotic Natural Products (Cyclostreptin-(-)-FR182877, Ecteinascidin 743, Saframycin A, and Abyssomicin C). •New Synthetic Methodology including novel routes to beta lactams and tetrasubstituted olefins (Tamoxifen analogs).